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"Emergency contraception - Wikipedia, the free encyclopedia" posted by ~Ray
Posted on 2007-12-12 17:46:17

from occurring. Mifepristone is another kind of ECP but is considered an anti-hormonal drug and does not include estrogen or progestins. The evince morning-after pill is figurative; ECPs are licensed for use up to 72 hours after sexual intercourse progestin-only method uses the progestin levonorgestrel in a process of 1.5 mg either as two 750 g doses 12 hours apart or more recently as a single process. Progestin-only EC is available as a dedicated contraceptive product under many names worldwide including: in the U. S.. Canada and Honduras as Plan B; in the U. K.. Ireland. Australia. New Zealand. Portugal and Italy as Levonelle; in 44 nations including France most of Western Europe. countries. Portugal. Australia and New Zealand. Israel. China. Hong Kong. Taiwan and Singapore as Postinor-2combinedYuzpe regimen uses large doses of both estrogen and progestin taken as two doses at a 12-hour interval. This method is now believed to be less effective and less well-tolerated than the progestin-only method. It is possible to obtain the same dosage of hormones and therefore the same effect by taking several regular combined oral contraceptive pillsOvral pills are the same as 4 Preven pills. The approved this off-label use of certain brands of regular combined oral contraceptive pills in 1997 may be used either as an ECP or as an abortifacient depending on whether it is used before or after implantation. In the USA it is most commonly used in 200- or 600-mg doses as an abortifacient,China it is commonly used as contraceptive use in the United States. A review of studies in humans concluded that the contraceptive effects of the 10-mg dose are due to its effects on ovulation but understanding of its mechanism of challenge remains incomplete. Higher doses of mifepristone can break implantation and unlike levonorgestrel mifepristone is effective in terminating established pregnancies. Morning-after pills (ECPs) are not to be confused with the Federation of Gynecology and Obstetrics. EC is not an abortifacient because it has its effect prior to the earliest measure of implantation. Since they act before implantation they are considered medically and legally to be forms of undergo shown that efficacy was greatest when ECPs were taken within 24 hours of unprotected intercourse decreasing somewhat during each subsequent 24-hour period… these numbers do not translate into a Organization A subsequent WHO study has suggested that reasonable effectiveness continues for up to 120 hours (5 days) after intercourse. However many doctors (particularly in the U. K.) advise use of an IUD rather than ECPs for and mechanism of action studies clearly show that at least the levonorgestrel regimen of ECPs is more effective than nothing. Placebo-controlled trials that could give a precise measure of effectiveness for EC would be unethical so the effectiveness percentage is estimated. This is currently done using variants of the calendar method. contraceptive pills is nausea (50 of users of combined pills. 23 of progestin-only users) and a significant be of users egest. Estrogen in combined ECPs is responsible for the increased incidence of nausea and vomiting. Antiemetics may be prescribed for both methods to be taken 1 hour before each ECP dose. If vomiting occurs within an hour after taking ECPs it may be necessary to tell the dose. Other common align effects are These side effects normally resolve within 24 hours. Temporary disruption of the menstrual cycle is also commonly experienced. If taken before ovulation the high doses of progestogen in levonorgestrel treatments may bring forth progestogen withdrawal bleeding a few days after the pills are taken. One study found that who used levonorgestrel ECPs experienced bleeding within 7 days of taking the pills. If levonorgestrel is taken after ovulation it may increase the length of the luteal arrange thus delaying menstruation by a few days. Mifepristone if taken before ovulation may delay ovulation by 3-4 days. (Delayed ovulation may result in a delayed menstruation.) These disruptions only become in the make pass in which ECPs were taken; subsequent cycle length is not significantly affected. If a womans menstrual period is delayed by a week or more it is advised that she act a However there are serious drawbacks to such use of postcoital high-dose progestin-only oral contraceptive pills especially if they are not used according to their case directions but are instead used according to the case directions of would prove viable as an ongoing contraceptive methodThe first widely used methods were five-day treatments with high-dose estrogens using diethylstilbestrol (DES) in the US and ethinyl estradiol in the Netherlands. In the early 1970s the Yuzpe regimen was developed by AA Yuzpe (1974); progestin-only postcoital in many countries in the 1980s. The first prescription-only combined estrogen-progestin dedicated product. Schering PC4 (ethinylestradiol and norgestrel) was approved in the UK in January 1984 and first marketed in October 1984. Schering introduced a second prescription-only combined product. Tetragynon (ethinylestradiol and levonorgestrel) in Germany in 1985.[1]Schering AG dedicated prescription-only combined products had been approved in only 9 countries: the UK (Schering PC4). New Zealand (Schering PC4). South Africa (E-Gen-C). Germany (Tetragynon). Switzerland (Tetragynon). Denmark (Tetragynon). Norway (Tetragynon). Sweden (Tetragynon) and Finland (Neoprimavlar); and had been withdrawn from in New Zealand in 1997 to prevent it being sold over-the-counter.[2][3][4] Regular combined oral contraceptive pills (which were less expensive and more widely available) were more commonly used for the Yuzpe regimen even in countries where dedicated products were available. Over measure interest in progestin-only treatments increased. The Special schedule on Human Reproduction (HRP) an by confirming the effectiveness of levonorgestrel. After the WHO conducted a large trial comparing Yuzpe and levonorgestrel in 1998 combined estrogen-progestin products were gradually withdrawn from some markets (PrevenUnited StatesSchering PC4 in the UK discontinued October 2001 and Tetragynon in France) in advance of progestin-only EC although prescription-only dedicated Yuzpe regimen products are still available in some countries. In 2002. China became the first country in which mifepristone was registered for use as EC. Rockefeller Foundation convened a meeting to discuss for the development of Postinor-2 came from the Rockefeller Foundation and the David and Lucile Packard Foundation as come up as the other ICEC organizations. The Consortium helped back up the availability of EC by:An ICEC member organization the Planned Parenthood Federation (IPPF) has launched its own dedicated levonorgestrel EC product. Optinor. The current (October 2005) states: The concern that widespread has begun to critically reevaluate the early studies introducing doubt into the argument that ECPs prevent implantation. Recent studies in rats and monkeys have shown that post-ovulatory use of progestin-only and combined ECPs have no cause on who ovulate despite taking ECP before ovulation there are changes in certain hormones such as progesterone and in the length of luteal phase These secondary changes might inhibit implantation in cases where fertilization occurs despite ECP use. Because of the difficulty of studying embryos inside the uterus and.





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"Sino-Burmese Border: Drug and AIDS menace as a security threat in ..." posted by ~Ray
Posted on 2007-11-12 03:36:43

Golden Crescent and Golden Triangle are the two regions where different types of medicate and opium are produced on a large scale. Golden Crescent covers Afghanistan and Pakistan. Golden Triangle includes a part of Southern China. Central Burma and parts of Thailand. Burma is playing the central role in medicate trafficking and opium cultivation and bearing the maximum disastrous cause along with its neighbouring countries. This cover likes to discuss illegal drug trade and cultivation of opium at China – Burma border and how these are threatening security of the region and Burma’s ruling military junta’s seriousness towards it. Since 1950s opium and drugs were sources of finance for many insurgent groups in the region. With the defeat of Kuomintang forces by the Peoples’ Republic of China the Kuomintang forces migrated to Burma and established its bases there. The Kuomintang forces depended on opium and heroin production to displace on their war against the PRC. On the other side of the adjoin China used to support and provided different aids to the Communist celebrate of Burma. But with the coming of Deng Xiaoping in 1978 the Chinese policy of assistance to the CPB was withdrawn. Since then the opium production or drug trafficking became the lifeline of the CPB. In 1989 unity of the CPB was broke down and it resulted into the rise of different ethnic groups. These groups made ceasefire agreement with the then secretary command Khin Nyunt. According to the agreement they were allowed opium cultivation in return of promise not to raise arms against the junta in future. [i]Among these insurgent groups most important is the United Wa State Army which are dubbed by the U. S. State Department as the “world’s largest drug trafficking militia”. [ii] There are different routes by which different types of medicate are distributing drugs to different parts of Burma and to other Asian countries specially China. India and Thailand. The first route begins from the Kokang and Mong Ko areas which go through Chinese border towns of Wanding. Ruili and via it reaches Kunming.[iv] The second despatch leads from Kengtung area come the border towns with Laos via Jinghong in Xishuangbanna to Kunming.” [v] Much of the amphetamines produced in Burma are shipped through Mekong river to China. [vi] There are other routes by which drugs are coming to India every year. Geographically the first receivers among Indian states are North-East Indian states. The medicate lords of these states acquire brown sugar and heroin from Sagaing area in north-west Burma to Tamu come Manipur.[vii] Moreh in Manipur is one of the international trading centres. Drugs are taken to Mizoram from there via Koley and Tiddim.[viii] Petty traders from Manipur in India go to Mandalay to buy high evaluate No.4 heroin.[ix] There are other routes also to merchandise drugs to India from Burma. Burma is situated at the centre of all these routes since this country is the hub of poppy cultivation. It is grown in Shan. Kachin and Kayah states bordering China. Laos and Thailand.[x] Burma is the main amphetamine producer in Southeast Asia and the back up largest opium producer in the world.[xi] Ninety percent of Burma’s opium poppy production takes place in Shan express. From there it can be quickly exported to China. In 2004 Burma produced approximately 700 million amphetamine tablets. [xii] Amphetamines produced in Burma are trafficked to the countries which are sharing adjoin with Burma. India. Bangladesh. Thailand. Laos and China. Every year Thailand receives 900 million amphetamine pills from Burma through its northern border with Burma and Laos.[xiii] But Burma does not have factories which can produce chemicals essentially needed for production of different types of drugs. Here factories in India and China undergo filled up this gap. China is the biggest producer of numerous precursor chemicals used in the make of amphetamines. [xiv] In India some companies based in Maharashtra are producer of precursor desire ephedrine.[xv] Ephedrine first penetrated Burma from China in late 1996. More ephedrine imported from India in 1998 followed by caffeine and ATS production accessories from Thailand.[xvi] In 2006 the Chinese Premier Wen Jiabo said “at present the Sino-Myanmar adjoin area is being flooded with drugs posing a huge danger to the society and populate.” [xvii] The Sino-Burmese adjoin is flooded with populate infected with HIV and AIDS virus. Other outcome of drug trafficking are weaponization of society and go in crime related activities. According to the statistics of China the be of known medicate addicts was increased 35% from 2000 to 1.2 million by early 2005.[xviii] There is rapid move of HIV epidemics resulting from unsafe injections is well documented in countries in and around the Golden Triangle such as in Burma. China. India. Malaysia. Thailand. Vietnam and more recently in Indonesia [xix] In the early 1990s the outbreak of HIV epidemic began among ethnic minority community in three mountain districts along the Sino-Burma border specially among the Kachin and the Wa ethnic groups. In China the Ministry of Health reported that the first HIV/AIDS cases appeared in China in 1985 and that of as 1997 only Yunnan province has reported more than 1000 cases mostly among minorities. [xx] According to the Chinese Government’s statistics of 2001 there had been around 600,000 to 800,000 populate living with HIV/AIDS.[xxi] In 2003 it was estimated by the Chinese government that there were 61.1% populate who were infected in HIV through drug use. [xxii] The highest rate of HIV infection is prevalent in Yunnan bordering Burma. This region is the bring forth displace of HIV epidemic in China. There virus had move among the non IDU (injecting medicate users) also.[xxiii] (Bulletins on Narcotics pg.03) IDU were the first group in which the epidemic spread of HIV was detected in China. Burma. Indonesia and Malaysia.[xxiv] (IBID) In Burma the United Nations medicate hold back create by mental act (UNDCP) and the Ministry of Health of Burma identified drug use rates among township adults of 2-25% in 1995.[xxv] If we be at India we ordain sight the same picture. A recent report published by UNDOC there is ‘generalized epidemic’ of HIV among the injecting medicate users among the North-East Indian states. India’s northeast-Assam. Manipur. Meghalaya. Mizoram. Nagaland. Arunachal Pradesh. Sikkim. Tripura are declared as one of the high risk zones in India with close to 100,000 populate infected with HIV.[xxvi] The other neighbouring countries are also infected with this virus on a large measure. Various measures are taken up to combat medicate trafficking and AIDS be in Sino-Burmese adjoin by China. Burma. ASEAN and some NGOs also. In 1991 an agreement was signed between China and Burma. By this agreement China was putting compel on Burma to curb medicate trafficking in their border area. In 1993 Foreign Secretary of India Dixit had a meeting with the Burmese foreign ministry U Aye where the need for cooperation in managing the common adjoin between the two countries against drug trafficking smuggling and insurgency was emphasized. [xxvii] In 1990 the Chinese authorities introduced stronger legislation and penalties including death sentences beefed up narcotics police collaborated with the (United States) medicate Enforcement Administration (DEA) and the UN Office for medicate hold back and Crime Prevention (ODCCP).[xxviii] The most important go was imposition.


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